Alcon Efrin - General Information:An alpha-adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent. [PubChem]
Other Brand Names containing Phenylephrine
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Alcon Efrin - Pharmacology:
Alcon Efrin is a powerful vasoconstrictor. It is used as a mydriatic, nasal decongestant, and cardiotonic agent. Alcon Efrin is a postsynaptic alpha-receptor stimulant with little effect on the beta receptors of the heart. Parenteral administration of Alcon Efrin causes a rise in systolic and diastolic pressures, cardiac output is slightly decreased and peripheral resistance is considerably increased, most vascular beds are constricted; renal, splanchnic, cutaneous, and limb blood flows are reduced but coronary blood flow is increased. Pulmonary vessels are constricted, and pulmonary arterial pressure is raised. This alpha receptor sympathetic agonist is also used locally because its vasoconstrictor and mydriatic action.
Alcon Efrin for patients
Alcon Efrin Interactions
Vasopressors, particularly metaraminol, may cause serious cardiac arrhythmias during halothane anesthesia and therefore should be used only with great caution or not at all.
The pressor effect of sympathomimetic pressor amines is markedly potentiated in patients receiving monoamine oxidase inhibitors (MAOI). Therefore, when initiating pressor therapy in these patients, the initial dose should be small and used with due caution. The pressor response of adrenergic agents may also be potentiated by tricyclic antidepressants.
Alcon Efrin Contraindications
Phenylephrine hydrochloride should not be used in patients with severe hypertension, ventricular tachycardia, or in patients who are hypersensitive to it or to any of the components.
Indication, Mechanism Of Action, Drug Interactions, Food Interactions, etc..