Blopress - General Information:

Blopress, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension. Blopress competes with angiotensin II for binding at the AT1 receptor subtype. As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance.

Related offer from MedStore:

AtacandGeneric Atacand (Candesartan) - 8mg 30 pills for $52.65
Atacand (Candesartan) is an angiotensin II receptor antagonist used to treat high blood pressure. It may also be used to treat congestive heart failure and other conditions as determined by your doctor.

Pharmacology:

Blopress, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension. Unlike the angiotensin receptor antagonist losartan, Blopress does not have an active metabolite or possess uricosuric effects.

Blopress for patients

Blopress Interactions

No significant drug interactions have been reported in studies of candesartan cilexetil given with other drugs such as glyburide, nifedipine, digoxin, warfarin, hydrochlorothiazide, and oral contraceptives in healthy volunteers, or given with enalapril to patients with heart failure (NYHA class II and III). Because candesartan is not significantly metabolized by the cytochrome P450 system and at therapeutic concentrations has no effects on P450 enzymes, interactions with drugs that inhibit or are metabolized by those enzymes would not be expected.

Lithiumó Reversible increases in serum lithium concentrations and toxicity have been reported during concomitant administration of lithium with ACE inhibitors, and with some angiotensin II receptor antagonists. An increase in serum lithium concentration has been reported during concomitant administration of lithium with ATACAND, so careful monitoring of serum lithium levels is recommended during concomitant use.

Blopress Contraindications

ATACAND is contraindicated in patients who are hypersensitive to any component of this product.

Additional information about Blopress

Blopress Indication: For the treatment of hypertension.
Mechanism Of Action: Blopress competes with angiotensin II for binding at the AT1 receptor subtype. As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance.
Drug Interactions: Amiloride Increased risk of hyperkaliemia
Drospirenone Increased risk of hyperkaliemia
Lithium The ARB increases serum levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Triamterene Increased risk of hyperkaliemia
Food Interactions: Take without regard to meals.
Administer on a regular basis, at about the same time each day.
Generic Name: Candesartan
Synonyms: Candesartan cilexetil
Drug Category: Antihypertensive Agents; Angiotensin II Receptor Antagonists
Drug Type: Small Molecule; Approved; Investigational
Other Brand Names containing Candesartan: Atacand; Blopress; Amias; Ratacand;
Absorption: Following administration of the candesartan cilexetil prodrug, the absolute bioavailability of candesartan was estimated to be 15%. Food with a high fat content has no affect on the bioavailability of candesartan from candesartan cilexetil.
Toxicity (Overdose): No lethality was observed in acute toxicity studies in mice, rats and dogs given single oral doses of up to 2000 mg/kg of candesartan cilexetil or in rats given single oral doses of up to 2000 mg/kg of candesartan cilexetil in combination with 1000 mg/kg of hydrochlorothiazide. In mice given single oral doses of the primary metabolite, candesartan, the minimum lethal dose was greater than 1000 mg/kg but less than 2000 mg/kg.
Protein Binding: Candesartan is highly bound to plasma proteins (>99%) and does not penetrate red blood cells.
Biotransformation: During absorption from the gastrointestinal tract, the prodrug candesartan cilexetil undergoes rapid and complete ester hydrolysis to form the active drug, candesartan. Elimination of candesartan is primarily as unchanged drug in the urine and, by the biliary route, in the feces. Minor hepatic metabolism of candesartan occurs by O -deethylation to form an inactive metabolite.
Half Life: Approximately 9 hours.
Dosage Forms of Blopress: Tablet Oral
Chemical IUPAC Name: 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
Chemical Formula: C24H20N6O3
Candesartan on Wikipedia: http://en.wikipedia.org/wiki/Candesartan
Organisms Affected: Humans and other mammals

Bookmark or Share this page


»Get link codes for this page«
(HTML/BB code)



Search by name browsing our [A-Z] index:

ABCDEFGHI
JKLMNOPQR
STUVWXYZ

Search by Categories:

See a list of all drugs for sale »

Top5 meds in current month:

*based on number of page views on Flexyx

Visit our friends:

brand and generic ed pills Russian Scientific Center for Restorative Traumatology and Orthopaedics in the name of academician G.A.Ilizarov

Related News

Mon, 29 Aug 2011
donde comprar Blopress Evansville - best price for generic Blopress where to buy
If this is your first visit, be sure to check out the FAQ by clicking the link above. You may have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. Results 1 to 1 of 1.
Source: forums.immigration.com »

Thu, 11 Aug 2011
Trying out BloPress - The Examined Life
Lifelogging, Less Waste, Decluttering. Determined to find an app to blog from, now trying BlogPress. It feels like sending an email. Yesterday we went to the Rosicrucian Egyptian Museum in San Jose. The larger pieces are casts from the British Museum, but still worth seeing.
Source: electriclawyer.typepad.com »

Sat, 23 Jul 2011
buy Blopress usa seller - over the counter Blopress 16 mg no prescription mexico
Hello There, Guest. Round Top Festival Institute Alumni Forum / My Category / My Forum / buy Blopress usa seller - over the counter Blopress 16 mg no prescription mexico. Order Blopress HERE -> ENTER PHARMACY 24/7 customer service We offer Blopress online for lowest prices.
Source: festivalhill.org »



Thanks for visiting us!