Brantur - General Information:

Brantur is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Brantur is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.

Pharmacology:

Brantur is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain. Similar to other antidepressant treatments, minaprine attenuates the beta-adrenergic receptor function. Studies have also shown that minaprine improves memory consolidation and that repeated drug administration leads to potentiation of this effect. Moreover, the effects of minaprine on memory consolidation are related to its dopaminergic action.

Additional information about Brantur

Brantur Indication: For the treatment of depression
Mechanism Of Action: Brantur binds to serotonin type 2 receptors and to dopamine D1 and D2 type receptors. It also binds to the serotonin reuptake pump. Therefore, minaprine blocks the reuptake of both dopamine and serotonin. It is also, to a slight degree, cholinomimetic. Thus it may exhibit both mood-brightening and nootropic properties.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Minaprine
Synonyms: Minaprine Hydrochloride; Minaprine Dihydrochloride; Minaprina [Inn-Spanish]; Minaprinum [Inn-Latin]
Drug Category: Antiparkinson Agents; Antidepressive Agents; Central Nervous System Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Minaprine: Brantur; Cantor;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatic. Cytochrome P4502D is responsible for the 4-hydroxylation of minaprine to 4-hydroxyminaprine.
Half Life: Not Available
Dosage Forms of Brantur: Not Available
Chemical IUPAC Name: 4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
Chemical Formula: C17H22N4O
Minaprine on Wikipedia: Not Available
Organisms Affected: Humans and other mammals

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