Corotrope - General Information:

A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase activity in myocardium and vascular smooth muscle. Corotrope is a derivative of amrinone and has 20-30 times the ionotropic potency of amrinone. [PubChem]

    Pharmacology:

    Corotrope, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

    Corotrope for patients

    Corotrope Interactions

    No untoward clinical manifestations have been observed in limited experience with patients in whom PRIMACOR was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements.

    Chemical Interactions

    There is an immediate chemical interaction which is evidenced by the formation of a precipitate when furosemide is injected into an intravenous line of an infusion of PRIMACOR. Therefore, furosemide should not be administered in intravenous lines containing PRIMACOR.

    Corotrope Contraindications

    PRIMACOR is contraindicated in patients who are hypersensitive to it.

    Other Brand Names containing Milrinone:

    Corotrop; Corotrope; Milrila; Primacor;

    Corotrope more info

    Indication, Mechanism Of Action, Drug Interactions, Food Interactions, etc..

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