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Daricon - General Information: Daricon is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers. Pharmacology: Daricon is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Daricon is an antimuscarinic, anticholinergic drug. Additional information about DariconDaricon Indication: For the treatment of peptic ulcer disease and the relief of smooth muscle spasms in gastrointestinal disorders. Mechanism Of Action: Daricon binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Oxphencyclimine inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Oxyphencyclimine Synonyms: Oxifencicliminum [Inn-Spanish]; Oxiphencycliminum; Oxyphencyclimine Hydrochloride; Oxyphencycliminum [Inn-Latin] Where to order Oxyphencyclimine (and Daricon analogs) online: Drug Category: Anticholinergic Agents; Antispasmodics Drug Type: Small Molecule; Approved Other Brand Names containing Oxyphencyclimine: Antulcus; Caridan; Cycmin; Daricol; Daricon; Dominil; Enterex; Gastrix; Manir; Naridan; Oximin; Setrol; Spazamin; Syklifen; Ulcociclinina; Vio-Thene; W-T Anticholinergic; Zamanil; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Daricon: Not Available Chemical IUPAC Name: (1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate Chemical Formula: C20H28N2O3 Oxyphencyclimine on Wikipedia: Not Available Organisms Affected: Humans and other mammals
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