Duratocin - General Information:
Duratocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.Pharmacology:
Duratocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is sold under the trade name Duratocin. It is an analogue of oxytocin, and its action is similar to that of oxytocin; it causes contraction of the uterus.Additional information about Duratocin
Duratocin Indication: Used to control postpartum hemorrhage and bleeding after giving birth.Mechanism Of Action: Duratocin binds to oxytocin receptors present on the smooth musculature of the uterus, resulting in rhythmic contractions of the uterus, increased frequency of existing contractions, and increased uterine tone. The oxytocin receptor content of the uterus is very low in the non-pregnant state, and increases during pregnancy, reaching a peak at the time of delivery.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Carbetocin
Synonyms: Carbetocinum [inn-latin]; Carbetocino [inn-spanish]
Drug Category: Anti-tocolytic Agents; Labor Induction Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Carbetocin: Duratocin;
Absorption: Bioavailability is 80% following intramuscular injection.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: 40 minutes
Dosage Forms of Duratocin: Liquid Intravenous
Chemical IUPAC Name: (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(3R,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-16-methyl-5,8,11,14,17-pentaoxo1-thia-4,7,10,13,16-pentazacycloicosane-3-carbonyl]pyrrolidine-2-carboxamide
Chemical Formula: C45H69N11O12S
Carbetocin on Wikipedia: http://en.wikipedia.org/wiki/Carbetocin
Organisms Affected: Humans and other mammals
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