Flexyx

Flexyx drugs: Dyflos

Dyflos - General Information:

An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330)

Pharmacology:

Dyflos is used as ocular drops in the treatment of chronic glaucoma. Dyflos is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Dyflos is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Dyflos damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.

Additional information about Dyflos

Dyflos Indication: For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Mechanism Of Action: The mechanism of isoflurophate's action involves the irreversible inhibition of cholinesterase.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Isoflurophate
Synonyms: DFP; Diflupyl; Diflurophate; Diisopropoxyphosphoryl Fluoride
Where to order Isoflurophate (and Dyflos analogs) online:
Drug Category: Antiglaucomic Agents; Ophthalmics; Cholinesterase Inhibitors; Miotics; Protease Inhibitors
Drug Type: Small Molecule; Approved
Other Brand Names containing Isoflurophate: Diisopropyl Fluoridophosphate; Diisopropyl Fluorophosphate; Diisopropyl Fluorophosphonate; Diisopropyl Phosphofluoridate; Diisopropyl Phosphorofluoridate; Diisopropylfluorfosfat; Disiopropyl Fluorophosphonate; Dyflos; Floropryl; Fluorodiisopropyl Phosphate; Fluoropryl; Fluostigmine; Fluropryl; Humorsol; Isofluorophate; Isofluorphate; Isoflurophosphate; Isopropyl Fluophosphate; Isopropyl Phosphorofluoridate; Neoglaucit; O,O-Diisopropyl Fluorophosphate; PF-3;
Absorption: Not Available
Toxicity (Overdose): Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Dyflos: Not Available
Chemical IUPAC Name: 2-(fluoro-propan-2-yloxyphosphoryl)oxypropane
Chemical Formula: C6H14FO3P
Isoflurophate on Wikipedia: http://en.wikipedia.org/wiki/Isoflurophate
Organisms Affected: Humans and other mammals