Flexyx

Flexyx drugs: Femcare

Femcare - General Information:

An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. [PubChem]

Related offers from our Drug Store:

Femcare 100 mg
Name	Quantity	Price (USD)	Order
Femcare 100mg	12 pills	51.8	Order
Femcare 100mg	18 pills	70.19	Order
Femcare 100mg	24 pills	83.94	Order

	Gyne-Lotrimin (Clotrimazole) - for $51.8 Gyne-Lotrimin is an antifungal agent used to treat vaginal yeast infections.
	Mycelex-G (Clotrimazole) - for $51.8 Mycelex-G is an antifungal agent used to treat vaginal yeast infections.

* >> all this drugs based on Clotrimazole (usually they can be used instead of Femcare)

Pharmacology:

Femcare, an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol, an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. Betamethasone and clotrimazole are used together to treat cutaneous tinea infections. In studies in fungal cultures, the minimum fungicidal concentration of clotrimazole caused leakage of intracellular phosphorous compounds into the ambient medium with concomitant breakdown of cellular nucleic acids, and accelerated potassium etflux. Both of these events began rapidly and extensively after addition of the drug to the cultures. The primary action of clotrimazole is against dividing and growing organisms.

Femcare for patients

How to use Clotrimazole :Use clotrimazole exactly as directed by your doctor. Always
read the manufacturer's information leaflet, if possible, before beginning treatment.
Clotrimazole preparations are usually applied two to three times a day until the
infection has cleared. This medicine is for you. Never give it to others, even if
their condition appears to be the same as yours. Getting the most from your
treatment : Always wash and dry your hands thoroughly before and after handling
clotrimazole. Do not allow clotrimazole to come into contact with the eyes, ears,
or mucous membranes (eg. mouth, vagina, inside of nose etc.), unless you are advised
to do so by your doctor. Complete the full course of treatment with clotrimazole,
otherwise your infection is likely to recur. Before using any 'over-the-counter'
medicines, check with your pharmacist which medicines are safe for you to use alongside
clotrimazole. You should see an improvement in your condition after a few days.
If your condition does not seem to be getting better after seven days, consult your
doctor for advice.

Femcare Interactions

No information provided.

Femcare Contraindications

Mycelex^Ò Troches are contraindicated in patients who are hypersensitive to any of its components.

Additional information about Femcare

Femcare Indication: For the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete's foot, and jock itch.
Mechanism Of Action: Femcare interacts with yeast 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the membrane. In this way, clotrimazole inhibits ergosterol synthesis, resulting in increased cellular permeability. Femcare may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms and the uptake of purine, impair triglyceride and/or phospholipid biosynthesis, and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Clotrimazole
Synonyms: Clotrimazol; Chlotrimazole
Where to order Clotrimazole (and Femcare analogs) online:
Drug Category: Anti-Infective Agents, Local; Antifungal Agents; Growth Inhibitors
Drug Type: Small Molecule; Approved
Other Brand Names containing Clotrimazole: Canesten; Canesten 1-Day Cream Combi-Pak; Canesten 1-Day Therapy; Canesten 3-Day Therapy; Canesten 6-Day Therapy; Canesten Combi-Pak 1-Day Therapy; Canesten Combi-Pak 3-Day Therapy; Canesten Cream; Canesten Solution; Canestine; Canifug; Cimitidine; Clotrimaderm; Empecid; FemCare; Gyne lotrimin; Gyne-Lotrimin 3; Gyne-Lotrimin 3 Combination Pack; Gyne-Lotrimin Combination Pack; Gyne-lotrimin; Gynix; Lotrimin; Lotrimin AF Cream; Lotrimin AF Jock-Itch Cream; Lotrimin AF Lotion; Lotrimin AF Solution; Lotrimin Af; Lotrimin Cream; Lotrimin Lotion; Lotrimin Solution; Mono-baycuten; Mycelax; Mycelex; Mycelex 7; Mycelex Cream; Mycelex G; Mycelex Solution; Mycelex Troches; Mycelex Twin Pack; Mycelex-7; Mycelex-7 Combination Pack; Mycelex-G; Myclo Cream; Myclo Solution; Myclo Spray Solution; Myclo-Gyne; Mycosporin; Mykosporin; Neo-Zol Cream; Trimysten; Trivagizole 3; Veltrim;
Absorption: Poorly and erratically absorbed orally, minimal vaginal or topical absorption.
Toxicity (Overdose): Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin, and cramps.
Protein Binding: 90%
Biotransformation: Hepatic (metabolized to inactive metabolites)
Half Life: 2 hours
Dosage Forms of Femcare: Cream Topical
Cream Intravaginal
Chemical IUPAC Name: 1-[(2-chlorophenyl)-di(phenyl)methyl]imidazole
Chemical Formula: C22H17ClN2
Clotrimazole on Wikipedia: http://en.wikipedia.org/wiki/Clotrimazole
Organisms Affected: Yeast and other fungi