Imidaline - General Information:

A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Imidaline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn. [PubChem]

Pharmacology:

Imidaline is a pulmonary vasodilator indicated used to decrease pulmonary vascular resistance (PVR) in persistent pulmonary hypertension of the newborn (PPHN).

Additional information about Imidaline

Imidaline Indication: For the treatment of pulmonary artery anomalies
Mechanism Of Action: Vasodilation by means of a direct effect on peripheral vascular smooth muscle and indirect effects produced, in part, by release of endogenous histamine; tolazoline has moderate alpha-adrenergic blocking activity and has histamine agonist activity. Imidaline usually reduces pulmonary arterial pressure and vascular resistance.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Tolazoline
Synonyms: Not Available
Where to order Tolazoline (and Imidaline analogs) online:
Drug Category: Vasodilator Agents; Antihypertensive Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Tolazoline: Artonil; Benzazoline; Benzidazol; Benzolin; Benzylimidazoline; Dilatol Asi; Divascol; Imidalin; Imidaline; Kasimid; Lambril; Olitensol; Peripherine; Phenylmethylimidazoline; Prefaxil; Priscol; Priscoline; Tolazolin; Vasimid; Vasodil; Vasodilatan;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Imidaline: Not Available
Chemical IUPAC Name: 2-(phenylmethyl)-4,5-dihydro-1H-imidazole
Chemical Formula: C10H12N2
Tolazoline on Wikipedia: http://en.wikipedia.org/wiki/Tolazoline
Organisms Affected: Humans and other mammals

Thanks for visiting us!