LYMErix (SmithKline Beecham) - General Information:
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant.Pharmacology:
LYMErix (SmithKline Beecham) is a single polypeptide chain of 270 amino acids. It is a vaccination used to prevent Lyme Disease.Additional information about LYMErix (SmithKline Beecham)
LYMErix (SmithKline Beecham) Indication: For prophylactic treatment of Lyme DiseaseMechanism Of Action: LYMErix (SmithKline Beecham), an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, is used to stimulate the production of specific antibodies against B. burgdorferi. B. burgdorferi. Therefore, it is used as a vaccination against Lyme Disease.s
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: OspA lipoprotein
Synonyms: Outer surface protein A precursor
Drug Category: Vaccines
Drug Type: Biotech; Approved
Other Brand Names containing OspA lipoprotein: LYMErix (SmithKline Beecham);
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: 1.2 hours (mammalian reticulocytes, in vitro).
Dosage Forms of LYMErix (SmithKline Beecham): Not Available
Chemical IUPAC Name: Borrelia outer surface protein A (OspA)
Chemical Formula: C1198H2012N322O422S2
OspA lipoprotein on Wikipedia: Not Available
Organisms Affected: Humans and other mammals
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