Lexilium - General Information:

One of the benzodiazepines that is used in the treatment of anxiety disorders. [PubChem] It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances.

Pharmacology:

Lexilium is a lipophilic, long-acting benzodiazepine and with sedative, hypnotic, anxiolytic and skeletal muscle relaxant properties. It does not possess any antidepressant qualities. Lexilium shares with other benzodiazepines the risk of abuse, misuse, psychological and/or physical dependence. According to many psychiatric experts Lexilium has a greater abuse potential than other benzodiazepines because of fast resorption and rapid onset of action.

Additional information about Lexilium

Lexilium Indication: For the short-term treatment of insomnia, short-term treatment of anxiety or panic attacks, if a benzodiazepine is required, and the alleviation of the symptoms of alcohol- and opiate-withdrawal.
Mechanism Of Action: Lexilium binds to the GABA receptor GABAA, causing a conformational change and increasing inhibitory effects of GABA. Other neurotransmitters are not influenced.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Bromazepam
Synonyms: 7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiaxepin-2(1H)-one; 7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiazepin-2(1H)-one; Bromazepamum [inn-latin]
Drug Category: Benzodiazepines; Hypnotics and Sedatives
Drug Type: Small Molecule; Illicit; Approved
Other Brand Names containing Bromazepam: Apo-Bromazepam; Calmepam; Compedium; Compendium; Creosedin; Durazanil; Gen-Bromazepam; Lectopam; Lekotam; Lexaurin; Lexilium; Lexomil; Lexotan; Lexotanil; Normoc; Novo-bromazepam; Nu-Bromazepam; Ultramidol; Somalium;
Absorption: Bioavailability is 84% following oral administration.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatically, via oxidative pathways (via an enzyme belonging to the Cytochrome P450 family of enzymes).
Half Life: 10-20 hours
Dosage Forms of Lexilium: Tablet Oral
Chemical IUPAC Name: 7-bromo-5-pyridin-2-yl-1,3-dihydro-1,4-benzodiazepin-2-one
Chemical Formula: C14H10BrN3O
Bromazepam on Wikipedia: http://en.wikipedia.org/wiki/Bromazepam
Organisms Affected: Humans and other mammals

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