Meprobamat - General Information:

A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamat has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia but has largely been superseded by the benzodiazepines. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) Meprobamat is a controlled substance in the U.S.

Related offer from MedStore:

AtaraxGeneric Atarax (Hydroxyzin) - 10mg 90 tabs for $58.73
Atarax (Hydroxyzine) is an antihistamine used to treat anxiety, to relieve itching caused by allergic conditions, and to cause drowsiness. It may also be used to treat other conditions as determined by your doctor.


Meprobamat is an anxiolytic drug. It was the best selling minor tranquilizer for a time but has largely been replaced by benzodiazepines. Meprobamat has most of the pharmacological effects and dangers of the barbiturates (though it was marketed as being safer). However, it is less sedating at effective doses. It is reported to have some anticonvulsant properties against absence seizures, but can exacerbate generalized tonic-clonic seizures. It has also been used as a hypnotic (sleeping pill). However, its is currently only licensed as an anxiolytic and it is a third or fourth-order choice.

Meprobamat for patients

Meprobamat Interactions

No Information Provided.

Meprobamat Contraindications

Acute intermittent porphyria as well as allergic or idiosyncratic reactions to meprobamate or related compounds such as carisoprodol, mebutamate, tybamate or carbromal.

Additional information about Meprobamat

Meprobamat Indication: For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety.
Mechanism Of Action: Meprobamat's mechanism of action is not known. It has been shown in animal studies to have effects at multiple sites in the central nervous system, including the thalamus and limbic system. Meprobamat binds to GABAA receptors which interrupt neuronal communication in the reticular formation and spinal cord, causing sedation and altered perception of pain.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Meprobamate
Synonyms: Meprobamat [German]; Meprobamatum [INN-Latin]; Meprobamato [Italian]; Meprobamato [INN-Spanish]; Meprobamic acid; DEA No. 2820; Procarbamide
Drug Category: Anti-anxiety Agents; Anticonvulsants; Hypnotics and Sedatives; Muscle Relaxants, Central
Drug Type: Small Molecule; Illicit; Approved
Other Brand Names containing Meprobamate: 3P bamate; Amepromat; Amosene; Anastress; Anathylmon; Anatimon; Andaksin; Andaxin; Aneural; Aneurol; Aneusral; Aneuxal; Aneuxral; Ansiatan; Ansietan; Ansil; Ansiowas; Anural; Anxietil; Anzil; Apascil; Apasil; Apo-Meprobamate; Appetrol; Appetrol-Sr; Arcoban; Arpon; Artolon; Ataraxine; Atraxin; Auxietil; Ayeramate; Ayermate; Bamate; Bamd 400; Bamo 400; Biobamat; Biobamate; Brobamate; Calmadin; Calmax; Calmiren; Canquil 400; Canquil-400; Carbaxin; Cirpon; Cirponyl; Coprobate; Crestanil; Cypron; Cyrpon; Dapaz; Deprol; Despasmol; Dicandiol; Diron; Diurnal; Diveron; Dormabrol; Ecuanil; Edenal; Enorden; Epicur; Epikur; Equagesic; Equanil; Equatrate; Equazine-M; Equilium; Equinil; Equitar; Erina; Estasil; Fas-Cile; Fas-Cile 200; Gadexyl; Gagexyl; Harmonin; Hartol; Holbamate; Ipsotian; Kesso-Bamate; Kessobamate; Klort; Larten; Lepenil; Lepetown; Letyl; Libiolan; Madiol; Mar-Bate; Margonil; Mendel; Mepamtin; Mepantin; Mepavlon; Mepiosine; Meposed; Mepranil; Mepriam; Meprin; Meprindon; Mepro-Aspirin; Mepro-analgesic; Meprobam; Meprobamat; Meproban; Meprocompren; Meprocon; Meprocon CMC; Meprodil; Meprodiol; Meprol; Meproleaf; Mepron; Mepronil; Meprosa; Meprosan; Meprosin; Meprospan; Meprotabs; Meprotan; Meprotanum; Meproten; Meprotil; Meprovan; Meprozine; Meptran; Mesmar; Metractyl; Metranquil; Micrainin; Milpath; Milprem; Miltamato; Miltann; Miltaun; Miltown; Miltrate; Miltuan; Miltwon; Misedant; Morbam; Multaun; My-trans; Neo-Tran; Nephentine; Nervonus; Neuramate; Oasil; Optarket; Orlevol; Orolevol; Pan-tranquil; Pancalma; Panediol; Pankalma; Pathibamate; Paxin; Pensive; Perequietil; Perequil; Perquietil; Pertranquil; Pimal; Placidon; Placitate; Prequil; Probamato; Probamyl; Probate; Procalmadiol; Procalmadol; Procalmidol; Promate; Promato; Proquanil; Protran; Q-Gesic; Quaname; Quanane; Quanil; Quietidon; Quivet; Rastenil; Reostral; Restenil; Restenyl; Restinal; Restinil; Restran; Robamate; SK-Bamate; Sadanyl; Scolazil; Sedabamate; Sedanil; Sedanyl; Sedazil; Sedoquil; Sedoselecta; Selene; Seril; Setran; Shalvaton; Solevione anastress; Sowell; Spantran; Stensolo; Tamate; Tensol; Tensonal; Trancot; Trankvilan; Tranlisant; Tranmep; Tranquil; Tranquilan; Tranquilate; Tranquilax; Tranquiline; Tranquillin; Tranquilsan; Tranquinol; Tranquisan; Trelmar; Urbil; Urbilat; Vio-Bamate; Vistabamate; Wardamate; Wyseals; Zirpon;
Absorption: Well absorbed from the gastrointestinal tract.
Toxicity (Overdose): Symptoms of overdose include coma, drowsiness, loss of muscle control, severely impaired breathing, shock, sluggishness, and unresponsiveness. Death has been reported with ingestion of as little as 12 g meprobamate and survival with as much as 40 g.
Protein Binding: Not Available
Biotransformation: Hepatic.
Half Life: Plasma half-life is about 10 hours.
Dosage Forms of Meprobamat: Tablet Oral
Chemical IUPAC Name: [2-(carbamoyloxymethyl)-2-methylpentyl] carbamate
Chemical Formula: C9H18N2O4
Meprobamate on Wikipedia:
Organisms Affected: Humans and other mammals

Bookmark or Share this page

»Get link codes for this page«
(HTML/BB code)

Search by name browsing our [A-Z] index:


Search by Categories:

See a list of all drugs for sale »

Top5 meds in current month:

*based on number of page views on Flexyx

Visit our friends:

brand and generic ed pills Russian Scientific Center for Restorative Traumatology and Orthopaedics in the name of academician G.A.Ilizarov

Related News

Sat, 11 Jun 2011
BioMedCentral - Intimal Hyperplasia in Balloon Dilated Coronary Arteries is Reduced by Local Delivery of the NO Donor, ...
Hypnosis was complemented with small intermittent doses of 5 mg meprobamat as needed. An 8 F introducer sheath (Cordis, USA) was inserted into the left carotid artery and 10,000 IU Heparin given.
Source: »

Mon, 04 Jan 2010
BioMed Central - Full text - Apyrase treatment of myocardial infarction according to a clinically applicable ...
During balanced anesthesia meprobamat (Mebumal, DAK, Copenhagen, Denmark) and thiopental (Pentothal, Abbott, Stockholm, Sweden), was titrated against animal requirements with small bolus doses.
Source: »

Mon, 26 Jan 1976
Carisoprodol (Soma) Facts -
Beermann B, Ohman B Meprobamat - huvudmetabolit tilll karisoprodol. Littrell RA, Sage T, Miller W Meprobamate dependence secondary to carisoprodol use. Reeves RR, Beddingfield JJ, Mack JE. Carisoprodol withdrawal syndrome. March 31, 2008 Last updated: April 25, 2011.
Source: »

Thanks for visiting us!