Metocarbamol - General Information:

A centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1206)

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Robaxin (Methocarbamol) is a muscle relaxant used to treat pain caused by muscle spasms.

Pharmacology:

Metocarbamol is a central muscle relaxant for skeletal muscles, used to treat spasms. It is structurally related to guaifenesin. Metocarbamol's exact mechanism of causing skeletal muscle relaxation is unknown. It is thought to work centrally, perhaps by general depressant effects. It has no direct relaxant effects on striated muscle, nerve fibers, or the motor endplate. It will not directly relax contracted skeletal muscles. The drug has a secondary sedative effect.

Metocarbamol for patients

Metocarbamol Interactions

No information available.

Metocarbamol Contraindications

Methocarbamol Tablets are contraindicated in patients hypersensitive to any of the ingredients.

Additional information about Metocarbamol

Metocarbamol Indication: For use as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions.
Mechanism Of Action: The mechanism of action of methocarbamol in humans has not been established, but may be due to central nervous system depression. It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber.
Drug Interactions: Not Available
Food Interactions: Avoid alcohol.
Generic Name: Methocarbamol
Synonyms: Not Available
Drug Category: Muscle Relaxants, Central
Drug Type: Small Molecule; Approved
Other Brand Names containing Methocarbamol: AHR 85; Avetil; Delaxin; Etroflex; Forbaxin; Glycerylguaiacolate carbamate; Glycerylguajacol-Carbamat; Guaiacol glyceryl ether carbamate; Guaiphenesin carbamate; Guaiphenesine carbamate; Lumirelax; Methocal; Metocarbamol; Metocarbamolo; Metofenia; Metofenina; Miolaxene; Miorilas; Miowas; Myolaxene; Neuraxin; Parabaxin; Perilax; Reflexyn; Relestrid; Robamol; Robaxan; Robaxin; Robaxine; Robaxon; Robinax; Romethocarb; Surquetil; Traumacut; Tresortil;
Absorption: Rapid. Onset of action is about 30 minutes after oral administration.
Toxicity (Overdose): Symptoms of overdose include blurred vision, coma, drowsiness, low blood pressure, nausea, and seizures.
Protein Binding: Not Available
Biotransformation: Hepatic.
Half Life: 1.14-1.24 hours
Dosage Forms of Metocarbamol: Tablet Oral
Liquid Intravenous
Liquid Intramuscular
Chemical IUPAC Name: [2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate
Chemical Formula: C11H15NO5
Methocarbamol on Wikipedia: http://en.wikipedia.org/wiki/Methocarbamol
Organisms Affected: Humans and other mammals

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