Norlestrin - General Information:

A synthetic progestational hormone with actions similar to those of progesterone but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception. [PubChem]

    Pharmacology:

    Norlestrin is a synthetic oral progestin. It is used for contraception or to treat such conditions as secondary amenorrhea, abnormal uterine bleeding, and endometriosis. As an oral contraceptive, norethindrone is available as either a single agent or in combination with an estrogen.

    Norlestrin for patients

    PATIENT INFORMATION

    INTRODUCTION

    This leaflet is about birth control pills that contain one hormone, a progestin. Please read this
    leaflet before you begin to take your pills. It is meant to be used along with talking with your
    doctor or clinic. Progestin-only pills are often called “POPs” or “the minipill”. POPs have less
    progestin than the combined birth control pill (or “the pill”) which contains both an estrogen and
    a progestin.

    HOW EFFECTIVE ARE POPs?

    About 1 in 200 POP users will get pregnant in the first year if they all take POPs perfectly (that is,
    on time, every day). About 1 in 20 “typical” POP users (including women who are late taking pills or
    miss pills) gets pregnant in the first year of use. Table 2 will help you compare the efficacy of
    different methods.

    DIALPAK® Tablet Dispenser-28’s

    The first time you use these pills, take your first pill on the first day of your menstrual period.
    Turn the ribbed outer ring clockwise until the day for your first pill is over the black Day Arrow in
    the center of the DIALPAK.
    To remove the pill, press down on it with your thumb or forefinger. The pill will drop through a hole
    in the bottom of the DIALPAK.
    On the next day, turn the ribbed outer ring clockwise to the next pill. The correct day will be indicated
    by the black Day Arrow in the center of the DIALPAK.
    Take one pill every day for 28 days, whether bleeding or not, until you have taken all the pills. It is
    important that you take your pill at the same time every day.
    After you have taken all 28 pills, begin taking your pills again the next day. Be sure the calendar day
    on your new package corresponds with the actual day.
    INSTRUCTIONS FOR USE VERIDATE® Tablet Dispenser-28’s

    Place the refill in the VERIDATE so that the V notch in the refill is at the top of the dispenser. Press
    the refill down so that it fits firmly under all nibs.
    The first time you use these pills, take your first pill on the first day of your menstrual period.
    Choose a pill that corresponds with the day of the week on which you are taking the first pill.
    Continue taking one pill daily, clockwise, until no pills remain in the outer circle. It is important that
    you take your pills at the same time every day.
    The next day, take a pill from the inner circle that corresponds with the day of the week it happens to be.
    Take a pill each day until all seven are taken.
    After you have taken all 28 pills, insert a new refill in the VERIDATE and begin taking your pills again
    the next day. Be sure the calendar day on the package corresponds with the actual day.

    WILL POPs AFFECT YOUR ABILITY TO GET PREGNANT LATER?

    If you want to become pregnant, simply stop taking POPs. POPs will not delay your ability to get pregnant.

    BREASTFEEDING

    If you are breastfeeding, POPs will not affect the quality or amount of your breastmilk or the health of
    your nursing baby.

    Norlestrin Interactions

    The effectiveness of progestin-only pills is reduced by hepatic enzyme-inducing drugs such as the anticonvulsants phenytoin, carbamazepine, and barbiturates, and the antituberculosis drug rifampin. No significant interaction has been found with broad-spectrum antibiotics.

    Norlestrin Contraindications

    Progestin-only oral contraceptives (POPs) should not be used by women who currently have the following conditions:

    • Known or suspected pregnancy
    • Known or suspected carcinoma of the breast
    • Undiagnosed abnormal genital bleeding
    • Hypersensitivity to any component of this product
    • Benign or malignant liver tumors
    • Acute liver disease

    Norlestrin more info

    Indication, Mechanism Of Action, Drug Interactions, Food Interactions, etc..