PMS-tiaprofenic - General Information:

PMS-tiaprofenic is a non-steroidal anti-inflammatory drug of the arylpropionic acid (profen) class, used to treat pain, especially arthritic pain.

Pharmacology:

PMS-tiaprofenic is a non-steroidal anti-inflammatory drug of the arylpropionic acid (profen) class, used to treat pain, especially arthritic pain. The typical adult dose is 300mg twice daily. It is not recommended in children.

Additional information about PMS-tiaprofenic

PMS-tiaprofenic Indication: Used to treat pain, especially arthritic pain.
Mechanism Of Action: PMS-tiaprofenic belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of a chemical (prostaglandin) which the body produces in response to injury or certain diseases. This prostaglandin would otherwise go on to cause swelling, pain and inflammation.
Drug Interactions: Not Available
Food Interactions: Avoid alcohol.
Take with food.
Generic Name: Tiaprofenic acid
Synonyms: 2-(5-Benzyl-2-thienyl)propionsaeure; 5-Benzoyl-alpha-methyl-2-thiopheneacetic acid; Acide tiaprofenique [inn-french]; Acido tiaprofenico [inn-spanish]; Acidum tiaprofenicum [inn-latin]; Tiaprofensaeure
Drug Category: Anti-Inflammatory Agents, Non-Steroidal
Drug Type: Small Molecule; Approved
Other Brand Names containing Tiaprofenic acid: Apo-Tiaprofenic Tablets; Dom-tiaprofenic; Novo-Tiaprofenic; Nu-Tiaprofenic; PMS-tiaprofenic; Surgam; Surgam SR; Tiaprofenic-200 - Tab; Tiaprofenic-300 - Tab;
Absorption: Bioavailability is 90% following oral administration.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatic (10%). Sparingly metabolised in the liver to two inactive metabolites.
Half Life: 1.5-2.5 hours
Dosage Forms of PMS-tiaprofenic: Capsule, extended release Oral
Tablet Oral
Chemical IUPAC Name: 2-[5-(benzoyl)thiophen-2-yl]propanoic acid
Chemical Formula: C14H12O3S
Tiaprofenic acid on Wikipedia: http://en.wikipedia.org/wiki/Tiaprofenic_acid
Organisms Affected: Humans and other mammals

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