Pre-Op - General Information:

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)


Pre-Op, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.

Pre-Op for patients

Pre-Op Interactions

No information available.

Pre-Op Contraindications

Do not use on burned or denuded skin; as an occlusive dressing, wet pack or lotion; as vaginal pack or tampon, on mucous membranes or for routine prophylactic total body bathing.

Should not be used on persons hypersensitive to any of its components nor on persons who have demonstrated primary light sensitivity to halogenated phenol derivatives because of the possibility of cross-sensitivity to hexachlorophene.

Additional information about Pre-Op

Pre-Op Indication: For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Mechanism Of Action: The primary mechanism of action of hexachlorophene, based on studies with Bacillus megatherium, is to inhibit the membrane-bound part of the electron transport chain, respiratory D-lactate dehydrogenase. It induces leakage, causes protoplast lysis, and inhibits respiration.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Hexachlorophene
Synonyms: Not Available
Drug Category: Anti-Infectives
Drug Type: Small Molecule; Approved
Other Brand Names containing Hexachlorophene: AT-7; Acigena; Almederm; Bilevon; Bivelon; Compound G-11; Cotofilm; Dermadex; Dial; Distodin; E-Z Scrub; Eleven; Exofene; Fascol; Fesia-Sin; Fomac; Fostril; G-Eleven; G-II; Gamophen; Gamophene; Germa-Medica; HCP; Hexa-Germ; Hexabalm; Hexachlorofen; Hexachlorophane; Hexachlorophen; Hexachlorophene, Pharma; Hexafen; Hexascrub; Hexazinone; Hexide; Hexophene; Hexosan; Isobac; Isobac 20; Nabac; Nabac 25 Ec; Neosept V; Phiso-Scrub; Phisodan; Phisohex; Pre-Op; Rcra Waste Number U132; Ritosept; Scrubteam Surgical Spongebrush; Septi-Soft; Septisol; Septofen; Soy-Dome; Ster-Zac; Steral; Steraskin; Surgi-Cen; Surgi-Cin; Surofene; Tersaseptic; Trichlorophene; Turgex;
Absorption: Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Toxicity (Overdose): Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Protein Binding: 92%
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Pre-Op: Emulsion Topical
Chemical IUPAC Name: 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)methyl]phenol
Chemical Formula: C13H6Cl6O2
Hexachlorophene on Wikipedia:
Organisms Affected: Enteric bacteria and other eubacteria

Bookmark or Share this page

»Get link codes for this page«
(HTML/BB code)

Search by name browsing our [A-Z] index:


Search by Categories:

See a list of all drugs for sale »

Top5 meds in current month:

*based on number of page views on Flexyx

Visit our friends:

brand and generic ed pills Russian Scientific Center for Restorative Traumatology and Orthopaedics in the name of academician G.A.Ilizarov

Related News

Fri, 11 May 2012
Corellian Run Radio - Operation - Information – Pre-Op Checklist
Information – Pre-Op Checklist. The Old Republic™ Podcast. This week I'd like to talk about your role as a member of an operation group and how to make sure you're never caught flat-footed for an ops run.
Source: »

Thu, 03 May 2012
Pre-op videos may ease recovery for cancer patients - Medical Marketing and Media - study
Promoting pain relief. Medical Marketing & Media. What-to-expect videos appear to minimize patient pain and increase surgery satisfaction, according to a study published in the May issue of the Journal of American College of Surgeons. MMM > News > Pre-op videos may ease recovery for cancer patients: study.
Source: »

Thu, 03 May 2012
Office Evaluation Comparable to Pre-Op Urodynamic Testing - MPR
Register for your FREE account now and join the thousands of healthcare professionals who have depended on us for over 26 years for accurate, concise, and timely drug information. Keep me logged in Forgot your password. More in Medical News.
Source: »

Thanks for visiting us!