Profenil - General Information:

Profenil is a smooth muscle relaxant. Smooth muscle is a type of muscle that is not under voluntary control; it is the muscle present in places such as the gut and uterus. Profenil acts directly on the muscle in the gut, causing it to relax. This prevents the muscle spasms which occur in the gut in conditions such as irritable bowel syndrome and diverticular disease. It is used to relieve cramps or spasms of the stomach and intestines. It is also useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.

Pharmacology:

Profenil is a smooth muscle relaxant. Smooth muscle is a type of muscle that is not under voluntary control; it is the muscle present in places such as the gut and uterus. Profenil acts directly on the muscle in the gut, causing it to relax. This prevents the muscle spasms which occur in the gut in conditions such as irritable bowel syndrome and diverticular disease. Diverticular disease is a condition in which small pouches form in the gut lining. These pouches can trap particles of food and become inflamed and painful. In irritable bowel syndrome the normal activity of the gut muscle is lost. The muscle spasms result in symptoms such as heartburn, abdominal pain and bloating, constipation or diarrhoea. By relaxing the gut muscle, alverine citrate relieves the symptoms of this condition. Profenil also relaxes the smooth muscle in the womb (uterus). It is therefore also used to treat painful menstruation, which is caused by muscle spasms in the uterus (dysmenorrhea).

Additional information about Profenil

Profenil Indication: Used to relieve cramps or spasms of the stomach and intestines. It is also useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Mechanism Of Action: Not Available
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Alverine
Synonyms: Alverina [inn-spanish]; Alverine citrate; Alverinum [inn-latin]; Bis(gamma-phenylpropyl)ethylamine; Di(phenylpropyl)ethylamine; N,N-Bis(3-phenylpropyl)ethylamine; N-Ethyl-3,3'-diphenyldipropylamine; N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine; N-Ethyl-bis(3-phenylpropyl)amin; N-Ethyl-N-(3-phenylpropyl)benzenepropanamine; Phenopropamine; Phenpropamine
Drug Category: Antispasmodics
Drug Type: Small Molecule; Approved
Other Brand Names containing Alverine: Antispasmin; Dipropylin; Dipropyline; Gamatran citrate; Profenil; Sestron; Spacolin; Spasmaverine;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Profenil: Not Available
Chemical IUPAC Name: N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine
Chemical Formula: C20H27N
Alverine on Wikipedia: Not Available
Organisms Affected: Humans and other mammals

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