Soxo - Pharmacology:

Soxo is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Soxo for patients

Sulfisoxazole should be taken with a full glass of water at regular intervals, 1 hour before and 2 hours after a meal. Finish the medication even if you already feel better. To prevent kidney damage, it is important to maintain adequate hydration, 2-3 L/day of fluids.

Sulfisoxazole may cause some side effects, for example:

  • dizziness
  • headache
  • photosensitivity
  • nausea, vomitting, or loss of appetite
  • sore throat, fever, vaginal itching or discharge, unusual bruising or bleeding, fatigue
  • blood in urine or change in urinary pattern
  • swelling of face, lips, or tongue

Talk to you doctor if you plan to become pregnant.

Soxo Interactions

Soxo Contraindications

Sulfisoxazole should not be given to patients who are hypersensitive to erythromycin, sulfonamides, or any component of the formulation, who have hepatic dysfunction, and porphyria. It is containdicated in infants of less than 2 months of age.

Sulfisoxazole can not be used concurrently with pimozide or cisapride.

Soxo more info

Indication, Mechanism Of Action, Drug Interactions, Food Interactions, etc..