Flexyx

Flexyx drugs: Talion

Talion - General Information:

Talion is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. Talion was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus in July 2000 and January 2002, respectively, and is marketed by Tanabe Seiyaku Co., Ltd. under the brand name Talion®. It is currently undergoing trials in the U.S.

Pharmacology:

Talion is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. It has a stabilizing effect on mast cells, and it suppresses the migration of eosinophils into inflamed tissues. Talion is under investigation in an eye drop formulation by Ista for the treatment of allergic conjunctivitis. An oral formulation of this drug is approved in Japan for the treatment of allergic conjunctivitis and uriticaria/puritus. Ista Pharm. filed an IND with the FDA for bepotastine in December of 2006.

Additional information about Talion

Talion Indication: For the treatment of allergic conjunctivitis and uriticaria/puritus.
Mechanism Of Action: Talion has three primary mechanisms of action. It is a non-sedating, selective antagonist of the histamine 1 (H1) receptor, it has a stabilizing effect on mast cells, and it suppresses the migration of eosinophils into inflamed tissues.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Bepotastine
Synonyms: Bepotastine besilate; Betotastine besilate; TAU-284DS
Drug Category: Antihistamines; Histamine H1 Antagonists, Non-Sedating; Anti-Allergic Agents
Drug Type: Small Molecule; Approved; Investigational
Other Brand Names containing Bepotastine: Talion;
Absorption: High oral absorption
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Talion: Tablet Oral
Solution / drops Ophthalmic
Chemical IUPAC Name: 4-[4-[(4-chlorophenyl)-pyridin-2-ylmethoxy]piperidin-1-yl]butanoic acid
Chemical Formula: C21H25ClN2O3
Bepotastine on Wikipedia: Not Available
Organisms Affected: Humans and other mammals