Teslac - General Information:An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer. [PubChem]
Other Brand Names containing Testolactone
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Teslac - Pharmacology:
Teslac is a synthetic anti-neoplastic agent that is structurally distinct from the androgen steroid nucleus in possessing a six-membered lactone ring in place of the usual five-membered carbocyclic D-ring. Despite some similarity to testosterone, testolactone has no in vivo androgenic effect. No other hormonal effects have been reported in clinical studies in patients receiving testolactone.
Teslac for patients
The physician should be consulted regarding missed doses. Notify the physician if adverse reactions occur or become more pronounced.
When administered concurrently, testolactone may increase the effects of oral anticoagulants; monitor and adjust anticoagulant dosage accordingly.
Drug/Laboratory Test Interactions: Physiologic effects of testolactone may result in decreased estradiol concentrations with radioimmunoassays for estradiol, increased plasma calcium concentrations, and increased 24-hour urinary excretion of creatine and 17-ketosteroids.
Testolactone is contraindicated in the treatment of breast cancer in men and in patients with a history of hypersensitivity to the drug.
Indication, Mechanism Of Action, Drug Interactions, Food Interactions, etc..