Thionex - General Information:

An organochlorine insecticide that has been used as a pediculicide and a scabicide. It has been shown to cause cancer. [PubChem]

    Pharmacology:

    Scabies is a common, highly pruritic infestation of the skin caused by Sarcoptes scabiei (lice). It is a very contagious condition with specific lesions, such as burrows, and nonspecific lesions, such as papules, vesicles and excoriations. The typical areas of the body it affects are finger webs, scalp (hair), wrists, axillary folds, abdomen, buttocks, inframammary folds and genitalia (males). It is characterized by intense night-time itching. Scabies is spread through close personal contact (relatives, sexual partners, schoolchildren, chronically ill patients and crowded communities). Scabies infestations and the corresponding symptoms can be eliminated by killing the scabies with topical insecticides or scabicides. Thionex is a scabicide that is essentially and organochloride insecticide.

    Thionex for patients

    http://www.fda.gov/cder/drug/infopage/lindane/lindaneQA.htm

    Thionex Interactions

    Oils may enhance absorption. Therefore, simultaneous use of creams, ointments or oils should be avoided.

    Thionex Contraindications

    Lindane Lotion is contraindicated for premature neonates because their skin may be more permeable than full term infants and their liver enzymes may not be sufficiently developed. It is also contraindicated for patients with Norwegian (crusted) scabies due to possible increased absorption. It is also contraindicated for patients with known seizure disorders and for individuals with a known sensitivity to the product or any of its components.

    Thionex more info

    Indication, Mechanism Of Action, Drug Interactions, Food Interactions, etc..

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