Tigan - General Information:

Tigan is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.

    Pharmacology:

    Tigan is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.

    Tigan for patients

    Tigan Interactions

    No specific information available.

     

    Tigan Contraindications

    Use of the injectable form of Tigan® in children, the suppositories in premature or newborn infants, and use of any dosage form in patients with known hypersensitivity to trimethobenzamide are contraindicated. Since the suppositories contain benzocaine they should not be used in patients known to be sensitive to this or similar local anesthetics.

    Other Brand Names containing Trimethobenzamide:

    Ametik hydrochloride; Benzacot; Nauseton; Stemetic; Tebamide; Tigan; Tribenzagan; Trimazide;

    Tigan more info

    Indication, Mechanism Of Action, Drug Interactions, Food Interactions, etc..