Tridone - General Information:

An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)

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Tridone - Pharmacology:

Paramethadione and trimethadione are anticonvulsants indicated in the control of absence (petit mal) seizures that are refractory to treatment with other medications. Dione anticonvulsants are used in the treatment of epilepsy. They act on the central nervous system (CNS) to reduce the number of seizures.

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Tridone Contraindications

Contraindicated in liver disease, kidney disease, retinal or optic nerve (eye) disease, a disease of the blood or bone marrow, and acute intermittent porphyria.

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