Turimycin A5 - General Information:

A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens. [PubChem]

Pharmacology:

Turimycin A5 is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.

Additional information about Turimycin A5

Turimycin A5 Indication: For the treatment of bacterial infections.
Mechanism Of Action: The mechanism of action of macrolides such as Turimycin A5 is via inhibition of bacterial protein biosynthesis by binding reversibly to the subunit 50S of the bacterial ribosome, thereby inhibiting translocation of peptidyl tRNA. This action is mainly bacteriostatic, but can also be bactericidal in high concentrations. Macrolides tend to accumulate within leukocytes, and are therefore actually transported into the site of infection.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Josamycin
Synonyms: Leucomycin A3; JM; Antibiotic yl-704 A3; Josamicina [inn-spanish]; Josamycine [inn-french]; Josamycinum [inn-latin]; Leucomycin V, 3-acetate 4(sup B)-(3-methylbutanoate); Leucomycin V, 3-acetate 4(sup beta)-(3-methylbutanoate); Leucomycin V, 3-acetate 4B-(3-methylbutanoate)
Where to order Josamycin (and Turimycin A5 analogs) online:
Drug Category: Antibacterial Agents; Macrolides
Drug Type: Small Molecule; Approved
Other Brand Names containing Josamycin: Josacine; Kitasamycin A3; Turimycin A5;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Turimycin A5: Not Available
Chemical IUPAC Name: [(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6S)-6-[[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-dimethylamino-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 3-methylbutanoate
Chemical Formula: C42H69NO15
Josamycin on Wikipedia: http://en.wikipedia.org/wiki/Josamycin
Organisms Affected: Enteric bacteria and other eubacteria

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