Flexyx

Flexyx drugs: Vasospan

Vasospan - General Information:

An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease. [PubChem]

Pharmacology:

Vasospan is a potent vasodilator (improves brain blood flow). On the cerebral level it prompts a lowering of vascular resistance, an increase in arterial flow and stimulates the use of oxygen and glucose. Vasospan also improves blood circulation in the lungs and limbs and has been shown to inhibit blood platelet aggregation.

Additional information about Vasospan

Vasospan Indication: For the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration.
Mechanism Of Action: Vasospan acts by inhibiting the postsynaptic alpha(1)-adrenoceptors on vascular smooth muscle. This inhibits the vasoconstrictor effect of circulating and locally released catecholamines (epinephrine and norepinephrine), resulting in peripheral vasodilation. Therefore the mechanism of Vasospan is to increase vascular circulation in the brain, thereby enhancing the transmission of nerve signals across the nerve fibres, which secrete acetylcholine as a neural transmitter.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Nicergoline
Synonyms: Not Available
Where to order Nicergoline (and Vasospan analogs) online:
Drug Category: Nootropic Agents; Vasodilator Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Nicergoline: MNE; Nargoline; Nicergolin [German]; Nicergolina [Dcit]; Nicergoline [Usan:Ban:Inn:Jan]; Nicergolinum [Inn-Latin]; Nicotergoline; Nimergoline; Nimergoline Base; Sermion; Vasospan;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Vasospan: Not Available
Chemical IUPAC Name: Not Available
Chemical Formula: C24H26BrN3O3
Nicergoline on Wikipedia: http://en.wikipedia.org/wiki/Nicergoline
Organisms Affected: Humans and other mammals