Flexyx

Flexyx drugs: Wy 8678 base

Wy 8678 base - General Information:

An alpha-2 selective adrenergic agonist used as an antihypertensive agent. [PubChem]

Pharmacology:

Wy 8678 base, a centrally acting α-2 adrenergic agonist, is indicated for treatment of hypertension.

Additional information about Wy 8678 base

Wy 8678 base Indication: For management of High blood pressure
Mechanism Of Action: Wy 8678 base's antihypertensive effect is thought to be due to central alpha-adrenergic stimulation, which results in a decreased sympathetic outflow to the heart, kidneys, and peripheral vasculature in addition to a decreased systolic and diastolic blood pressure and a slight slowing of pulse rate. Chronic administration of guanabenz also causes a decrease in peripheral vascular resistance.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Guanabenz
Synonyms: Not Available
Where to order Guanabenz (and Wy 8678 base analogs) online:
Drug Category: Sympatholytics; Antihypertensive Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Guanabenz: GBZ; Guanabenz Acetate; Guanabenz [USAN:INN]; Guanabenz(USAN); Guanabenzo [INN-Spanish]; Guanabenzum [INN-Latin]; Wy 8678 base; Wytensin;
Absorption: Approximately 75% absorbed from gastrointestinal tract
Toxicity (Overdose): Excessive contraction of the pupils, irritabilitylow blood pressure, sleepiness, slow heartbeat, sluggishness
Protein Binding: 90%
Biotransformation: Hepatic
Half Life: 6 hours.
Dosage Forms of Wy 8678 base: Not Available
Chemical IUPAC Name: 2-[(2,6-dichlorophenyl)methylideneamino]guanidine
Chemical Formula: C8H8Cl2N4
Guanabenz on Wikipedia: http://en.wikipedia.org/wiki/Guanabenz
Organisms Affected: Humans and other mammals